Matthias Griese Selected Research

Surfactant Dysfunction

3/2018	Chronic interstitial lung disease in children.
1/2018	ABCA3 missense mutations causing surfactant dysfunction disorders have distinct cellular phenotypes.
12/2016	Tools to explore ABCA3 mutations causing interstitial lung disease.
1/2016	Surfactant proteins in pediatric interstitial lung disease.

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Matthias Griese Research Topics

Disease

40	Cystic Fibrosis (Mucoviscidosis) 11/2021 - 09/2003
35	Lung Diseases (Lung Disease) 03/2022 - 06/2002
25	Interstitial Lung Diseases (Interstitial Lung Disease) 12/2021 - 04/2004
20	Pulmonary Alveolar Proteinosis 01/2022 - 04/2004
15	Inflammation (Inflammations) 11/2021 - 02/2002
9	Asthma (Bronchial Asthma) 10/2016 - 04/2004
8	Disease Progression 01/2022 - 11/2013
4	Pneumonia (Pneumonitis) 01/2021 - 02/2003
4	Infections 01/2021 - 10/2006
4	Allergic Bronchopulmonary Aspergillosis 01/2020 - 06/2006
4	Surfactant Dysfunction 03/2018 - 01/2016
4	Chronic Obstructive Pulmonary Disease (COPD) 10/2016 - 12/2007
4	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 08/2016 - 09/2006
4	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2016 - 08/2005
4	Ciliary Motility Disorders (Primary Ciliary Dyskinesia) 01/2016 - 07/2006
3	Bronchiectasis 11/2022 - 01/2016
3	Fibrosis (Cirrhosis) 10/2021 - 01/2016
3	Body Weight (Weight, Body) 04/2021 - 11/2005
3	Respiratory Tract Infections (Respiratory Tract Infection) 04/2020 - 01/2007
3	Rare Diseases (Rare Disease) 10/2019 - 11/2005
3	Protein C Deficiency 07/2015 - 03/2014
3	Respiratory Insufficiency (Respiratory Failure) 06/2014 - 04/2004
3	Lung Injury 09/2011 - 06/2002
3	Gastroesophageal Reflux (GERD) 11/2007 - 06/2002
3	Hypersensitivity (Allergy) 12/2006 - 04/2004
2	Respiratory Sounds (Crackle) 12/2021 - 01/2007
2	Neoplasms (Cancer) 11/2021 - 06/2002
2	Extrinsic Allergic Alveolitis (Hypersensitivity Pneumonitis) 03/2018 - 01/2017
2	Dyspnea (Shortness of Breath) 01/2018 - 10/2015
2	Failure to Thrive 10/2015 - 07/2015
2	Cough 10/2015 - 11/2013
2	Pseudomonas Infections 12/2014 - 02/2002
2	Chronic Cough 05/2007 - 04/2005
1	Communicable Diseases (Infectious Diseases) 11/2022
1	Agammaglobulinemia (Hypogammaglobulinemia) 01/2022
1	Tachypnea 12/2021
1	Angiomatosis 10/2021
1	Virus Diseases (Viral Diseases) 01/2021
1	Seizures (Absence Seizure) 01/2021

Drug/Important Bio-Agent (IBA)

33	Surface-Active Agents (Surfactants)IBA 01/2022 - 01/2002
24	Proteins (Proteins, Gene)FDA Link 10/2021 - 06/2002
7	LipidsIBA 11/2019 - 04/2004
7	Biomarkers (Surrogate Marker)IBA 10/2017 - 01/2011
7	Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA 01/2016 - 01/2002
6	Protein CIBA 01/2018 - 04/2005
5	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2020 - 08/2014
5	Pulmonary Surfactants (Pulmonary Surfactant)IBA 08/2017 - 01/2002
4	EnzymesIBA 11/2021 - 06/2002
4	ivacaftorIBA 01/2021 - 11/2011
4	Adenosine Triphosphate (ATP)IBA 01/2018 - 08/2016
4	ChitinasesIBA 10/2017 - 01/2011
4	Glutathione (Reduced Glutathione)IBA 05/2017 - 04/2004
4	Anti-Bacterial Agents (Antibiotics)IBA 01/2016 - 06/2002
4	ChemokinesIBA 12/2014 - 04/2005
3	Messenger RNA (mRNA)IBA 01/2021 - 05/2007
3	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 01/2021 - 11/2011
3	AntioxidantsIBA 05/2017 - 04/2004
3	Dyneins (Dynein)IBA 01/2016 - 07/2006
3	AerosolsIBA 01/2016 - 04/2004
3	AntibodiesIBA 08/2015 - 02/2002
3	SteroidsIBA 11/2013 - 11/2004
2	Immunoglobulins (Immunoglobulin)IBA 01/2022 - 06/2002
2	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2021 - 05/2007
2	CholesterolIBA 01/2021 - 06/2014
2	InterferonsIBA 01/2021 - 01/2013
2	Drug CombinationsIBA 01/2021 - 06/2014
2	ivacaftor drug combination tezacaftorIBA 01/2021 - 01/2018
2	Methionine-tRNA LigaseIBA 11/2020 - 05/2015
2	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 04/2020 - 04/2015
2	Oxygen (Dioxygen)IBA 04/2020 - 01/2018
2	Phospholipids (Phosphatides)FDA LinkGeneric 11/2019 - 01/2015
2	AutoantibodiesIBA 10/2019 - 12/2015
2	Amino Acyl-tRNA Synthetases (Aminoacyl-tRNA Synthetase)IBA 10/2019 - 01/2018
2	Lipoproteins (Lipoprotein)IBA 10/2019 - 04/2013
2	Phosphatidylcholines (Phosphatidylcholine)IBA 09/2016 - 09/2011
2	Leukocyte Elastase (Neutrophil Elastase)IBA 01/2016 - 01/2010
2	Acetaminophen (Paracetamol)FDA LinkGeneric 06/2015 - 08/2014
2	DNA (Deoxyribonucleic Acid)IBA 01/2015 - 06/2014
2	Immunoglobulin G (IgG)IBA 11/2013 - 10/2006
2	Chemokine ReceptorsIBA 06/2012 - 12/2008
2	Tobramycin (Nebcin)FDA LinkGeneric 03/2008 - 02/2002
2	Pulmonary Surfactant-Associated Protein CIBA 01/2008 - 04/2004
2	ProteomeIBA 10/2007 - 06/2002
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 11/2004 - 02/2002
1	SolutionsIBA 03/2022
1	Bronchodilator Agents (Bronchodilators)IBA 12/2021
1	Glutathione Transferase (Glutathione S-Transferase)IBA 11/2021
1	nintedanibIBA 04/2021
1	ivacaftor drug combination lumacaftorIBA 01/2021
1	elexacaftorIBA 01/2021
1	Nucleic AcidsIBA 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	Interferon Type IIBA 01/2021

Therapy/Procedure

14	Therapeutics 12/2021 - 10/2004
2	Hematopoietic Stem Cell Transplantation 01/2022 - 05/2011
2	Lung Transplantation 01/2020 - 03/2018
2	Nebulizers and Vaporizers (Inhaler) 06/2014 - 04/2004
1	Primary Care Nursing 11/2022
1	Injections 01/2022
1	Drug Tapering 04/2021